Learn about early diabetes symptoms, diabetic diet information, diabetes care, type 1 diabetes, insulin resistance and type 2 diabetes. Read the latest medical research on diabetes.
People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria, a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study.
Posted: January 19, 2017, 9:34 pm
A team led by scientists has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins.
Posted: January 19, 2017, 5:54 pm
Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks researchers have found.
Posted: January 19, 2017, 5:02 pm
Statins could hold the key to eradicating one of the most preventable causes of hospital deaths after researchers uncovered a new role for the cholesterol-lowering pill.
Posted: January 19, 2017, 3:02 pm
Gestational diabetes raises the risk of postpartum depression in first-time mothers, researcher have concluded.
Posted: January 18, 2017, 5:52 pm
Treatment for certain diabetes cases involves constant monitoring of blood-glucose levels and daily insulin shots. But scientists are now developing a painless 'smart' patch that monitors blood glucose and releases insulin when levels climb too high. The device has been tested on mice.
Posted: January 18, 2017, 3:38 pm
Researchers address the possible but unproven link between statins and diabetes, as well as the implications of prescription of statins for clinicians and their patients. They emphasize that the risk of diabetes, even if real, pales in comparison to the benefits of statins in both the treatment and primary prevention of heart attacks and strokes.
Posted: January 18, 2017, 1:34 pm
Researchers have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.
Posted: January 18, 2017, 12:27 am
An FDA-approved drug has been identified that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and lower body weight gain, even after being fed a high-calorie diet. The researchers say the technique, which uses cellular reprogramming, could be a new way to combat obesity and type II diabetes.
Posted: January 17, 2017, 7:01 pm
As commuters shimmy past large, lumbering trucks on the road, they may glance over and wonder, “How safe is that driver next to me?” If the truck driver is in poor health, the answer could be: Not very. Commercial truck drivers with three or more medical conditions double to quadruple their chance for being in a crash than healthier drivers, reports a new study.
Posted: January 17, 2017, 1:38 pm
When we eat, we do not just take in nutrients -- we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria. This triggers an inflammatory response that activates the immune systems of healthy individuals and has a protective effect, as doctors have proven for the first time. In overweight individuals, however, this inflammatory response fails so dramatically that it can lead to diabetes.
Posted: January 16, 2017, 5:19 pm
A urine test has been developed that measures the health of a person's diet. This test could be the first independent indicator of the quality of a person's diet, and what they are really eating, say the researchers.
Posted: January 13, 2017, 2:59 am
Can your smart watch detect when you are becoming sick? A new study indicates that this is possible. By following 60 people through their everyday lives, researchers found that smart watches and other personal biosensor devices can help flag when people have colds and even signal the onset of complex conditions like Lyme disease and diabetes.
Posted: January 12, 2017, 7:11 pm
People with early schizophrenia are at an increased risk of developing diabetes, even when the effects of antipsychotic drugs, diet and exercise are taken out of the equation, according to a new analysis.
Posted: January 12, 2017, 4:57 pm
Just one session of interval weight-training can improve the risk of Type 2 diabetes complications, according to a new study. This is encouraging news for those starting the New Year with good intentions.
Posted: January 11, 2017, 2:14 pm
Researchers are developing a portable device for detecting type 1 or type 2 diabetes at an early stage. The ultimate aim of the project is to develop a prototype of the device.
Posted: January 10, 2017, 5:11 pm
New findings may one day help clinicians predict the outcome of roux-en-Y gastric bypass surgery.
Posted: January 10, 2017, 5:06 pm
Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver. Such changes in DNA methylation are also detectable in humans with fatty liver and suggest a similar causal chain.
Posted: January 9, 2017, 3:24 pm
A new health link has been found between short sleep during pregnancy and gestational diabetes mellitus (GDM). This is the first study to examine the relationship between sleep duration and GDM in a multi-ethnic Asian population. Findings suggest that addressing sleep concerns during pregnancy could potentially reduce the risk of developing GDM.
Posted: January 9, 2017, 2:26 pm
People with any form of diabetes are at greater risk of developing cardiovascular conditions than people without the disease. Moreover, if they undergo an operation to open up a clogged artery by inserting a 'stent' surgical tube, the artery is much more likely to clog up again. However, researchers now have uncovered an explanation for why these procedures often fail, which may lead toward better alternatives.
Posted: January 5, 2017, 12:23 am
Participants in the Why WAIT (Weight Achievement and Intensive Management) program lost substantial amounts of weight, and even those who maintained relatively little loss of weight after five years demonstrated reduced risks of cardiovascular disease.
Posted: January 4, 2017, 8:43 pm
Sugar-free and “diet” drinks are often seen as the healthier option, but researchers have argued that they are no more helpful for maintaining a healthy weight than their full-sugar versions.
Posted: January 3, 2017, 8:10 pm
A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease (NAFLD) in the offspring of obese mice.
Posted: January 3, 2017, 5:23 pm
Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism. Researchers were able to predict this effect based on computer simulations and then confirm it with experiments.
Posted: January 3, 2017, 3:18 pm
Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin. Thus, physical activity helps to reduce the risk of developing diabetes, while also reducing the effects of diabetes if it does set in. Until now, no one has understood the underlying mechanism of this phenomenon.
Posted: January 3, 2017, 2:20 pm
Starting a regular program at the gym is a common New Year's resolution, but it's one that most people are unable to stick with for very long. Now a study done in mice is providing clues about one of the reasons why it may be hard for so many people to stick with an exercise program. The investigators found that in obese mice, physical inactivity results from altered dopamine receptors rather than excess body weight.
Posted: December 29, 2016, 7:19 pm
Leveraging existing relationships with friends and family may be a more effective way to improve patients' health and encourage new healthy habits and behaviors than increasing interactions with physicians or other clinicians. In a new perspective article, behavioral economists suggest a five-step ladder to effectively engineering social engagements that promote health and to test their acceptability and effectiveness.
Posted: December 29, 2016, 4:34 pm
A new study shows that the drug fenofibrate might reduce the risk of cardiovascular events in patients with type 2 diabetes who have high levels of triglycerides and low levels of 'good' cholesterol, despite being treated with statins.
Posted: December 28, 2016, 8:59 pm
A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells. The team of researchers has also reported that specific cancer cells respond to this combination of drugs.
Posted: December 27, 2016, 1:35 pm
Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists.
Posted: December 23, 2016, 4:59 pm
The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA, concludes a large-scale international study. The study shows that a high BMI leads to epigenetic changes at nearly 200 loci of the genome – with effects on gene expression.
Posted: December 22, 2016, 2:48 pm
Approximately 2,200 Americans die each day from heart attacks, strokes and other cardiovascular diseases. The most common cause is blocked blood vessels that can no longer supply oxygen and nutrients to the heart and brain. A recent study has shown that a protein inhibitor drug prevents these blockages, and could be a new therapeutic approach to prevent heart attack, stroke and other diseases caused by blocked blood vessels.
Posted: December 21, 2016, 7:13 pm
A high fat diet alone is not enough to cause metabolic syndrome, a group of symptoms that pose as risk factors for diabetes and heart disease. This recent study shows it is needed in combination with vitamin D deficiency. Accordingly, vitamin D supplementation improves metabolic syndrome in mice. The next step would be to validate the results in humans.
Posted: December 21, 2016, 5:54 pm
A bionic pancreas system has proven better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, in a clinical trial.
Posted: December 20, 2016, 2:51 pm
The NHS Health Check programme in England may have prevented an estimated 4,600 to 8,400 heart attacks, strokes, or death from these causes in its first five years, according to an independent review of the program.
Posted: December 20, 2016, 3:06 am
Higher levels of the enzyme, autotaxin, significantly predict memory impairment and type 2 diabetes. The research emphasizes the link between physical and mental health.
Posted: December 19, 2016, 6:44 pm
A recent paper examines how cells recovering from damage induced by a high-fat diet can be treated with a drug for type 2 diabetes called metformin to reverse the effects of metabolic memory.
Posted: December 19, 2016, 6:38 pm
The human microbiome appears to play a significant role in health and disease, but the mechanisms of how it does so is not well understood. Researchers have used the nematode C. elegans to decipher how specific bacterial signals influence a host, whether the host is a worm or a human. It reveals for the first time how bacterial genes modify worm biology, with implications for future study of the human microbiome.
Posted: December 16, 2016, 5:16 pm
Reducing sugar content of high and mid sugar drinks is likely to have the greatest impact on health, with fewer cases of obesity, diabetes and tooth decay. The UK soft drinks industry levy, due to be introduced in April 2018, is estimated to have significant health benefits, especially among children, according to the first study to estimate its health impact.
Posted: December 16, 2016, 12:16 am
Strokes and heart attacks are rare for women with diabetes who use hormonal contraception, with the safest options being intrauterine devices (IUDs) and under-the-skin implants, new research shows.
Posted: December 15, 2016, 7:33 pm
Gene variants associated with disease are typically considered faulty, and problems arise when the proteins they make don't adequately carry out their designated role, report scientists.
Posted: December 15, 2016, 5:47 pm
A new discovery offers new insight into regulation of water and food intake. Neuroscientists recorded neuronal activity in real-time in awake mice when presented with food or water, and identified anticipatory changes in neuronal activity in the seconds prior to drinking.
Posted: December 15, 2016, 5:47 pm
Scientist have demonstrated for the first time that their peptide-hydrogel biomaterial prompts skin cells to 'crawl' toward one another, closing chronic, non-healing wounds often associated with diabetes, such as bed sores and foot ulcers.
Posted: December 14, 2016, 2:03 pm
A newly discovered bacterial protein produced in the zebrafish gut triggers insulin-producing beta cells of the pancreas to multiply during early larval development, say researchers. The research potentially has human health implications. The findings, which could someday lead to new diabetes treatments, highlight the important role of resident microbes in development of the pancreas,
Posted: December 13, 2016, 6:06 pm
A famine that afflicted China between 1959 and 1961 is associated with an increased hyperglycemia risk not only among people who were born then, but also among the children they had a generation later.
Posted: December 12, 2016, 4:57 pm
Certain type 2 diabetes drugs promote weight loss, but how they do this remains poorly understood. Insight into how these drugs work in the body -- and especially the brain -- could help create new drugs that effectively control body weight. In an important advance on that front, a new study shows that these drugs, called glucagon-like peptide-1 receptor agonists (GLP-1RAs), reduce body mass by targeting a different part of the brain than previously thought.
Posted: December 11, 2016, 12:42 pm
Blood flows preferentially to the placenta instead of the brain in fetuses of mothers with diabetes, reveals new research.
Posted: December 11, 2016, 12:41 pm
Researchers show that moderate exercise may improve hippocampal memory dysfunction caused by type 2 diabetes and that enhanced transport of lactate to neurons may be the underlying mechanism.
Posted: December 9, 2016, 1:06 pm
Researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.
Posted: December 8, 2016, 7:33 pm
New research revealed contrasting roles for the SNAP23 protein in pancreatic secretion of digestive enzymes and hormones such as insulin. Inhibiting SNAP23 with a potential new diabetes drug enabled an alternative related protein of higher efficacy to compensate for its function and increase insulin secretion in mice. The novel therapy also shows promise as a treatment for pancreatitis.
Posted: December 8, 2016, 5:59 pm
A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of new research.
Posted: December 7, 2016, 7:32 pm
The browning program in white fat cells is normally suppressed by a protein called FLCN, researchers have found. It performs this function in cooperation with a major cellular signaling hub, a protein complex known as mTOR. Harnessing this knowledge may one day provide the key to better treatments for obesity.
Posted: December 6, 2016, 5:52 pm
A novel route for non-covalent protein modification has now been tested, and results reveal a new way to improve the stability of common protein drugs and extend shelf-life.
Posted: December 2, 2016, 8:08 pm
FDA-approved artemisinins, which have been used for decades to treat malaria, transform glucagon-producing alpha cells in the pancreas into insulin producing cells, researchers report.
Posted: December 1, 2016, 5:17 pm
Researchers have studied variants in the genes encoding HMGCR (the target of statins) and PCSK9 (the target of PCSK9 inhibitors) that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol.
Posted: December 1, 2016, 4:59 pm
With the help of the CRISPR/Cas9 gene scissors, researchers have managed to “turn off” an enzyme that proved to play a key role in the regulation of the diabetes-associated TXNIP gene. The results are decreased cell death and increased insulin production in the genetically modified pancreatic beta cells.
Posted: December 1, 2016, 2:30 pm
A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to scientists.
Posted: November 30, 2016, 8:45 pm
The intestinal bacterium Akkermansia proves to offer enduring benefits for the intestines of overweight mice and diabetic animals. In experiments, the strengthening effects of this bacterium on the intestinal barrier remained even after pasteurisation. These results help to pave the way for treatments against diabetes and obesity, but also against cardiovascular diseases and gastroenteritis.
Posted: November 30, 2016, 3:40 pm
Even mildly elevated body iron contributes to the prevalence and incidence of type 2 diabetes, according to research. Excess body iron accumulation is a known risk factor of type 2 diabetes in hereditary hemochromatosis, but these results show that elevated iron is a risk factor in the general population as well, already at high levels within the normal range.
Posted: November 30, 2016, 1:50 pm
New research by a mathematics professor has successfully reactivated oscillations in insulin-producing pancreatic beta cells — one of the first necessary steps to resurrecting the dormant cells and restoring the production of insulin.
Posted: November 29, 2016, 7:34 pm