Learn about early diabetes symptoms, diabetic diet information, diabetes care, type 1 diabetes, insulin resistance and type 2 diabetes. Read the latest medical research on diabetes.
A new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice has been discovered by researchers. Their study suggests that inhibiting this molecule may prevent similarly aberrant blood vessels from damaging the vision of not only diabetics, but also premature infants.
Posted: March 22, 2017, 2:49 pm
For parents, storing their newborn baby's umbilical cord blood is a way to preserve potentially lifesaving cells. Now, a group of researchers has found a way to expand and preserve certain cord-blood cells as a potential treatment for type 1 diabetes.
Posted: March 22, 2017, 2:36 pm
Insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance, new research suggests.
Posted: March 21, 2017, 4:25 pm
Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours. The circadian clock therefore describes the internal system that allows us to anticipate the changes of day and night by regulating nearly all the aspects of our physiology and behavior. At a time when our biological rhythms are increasingly undermined - whether by night work, jetlag, or societal habits, - scientists begin to unveil the impact such circadian misalignments may have in the explosion of metabolic diseases.
Posted: March 20, 2017, 1:04 pm
How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks, say investigators.
Posted: March 17, 2017, 5:16 pm
Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study.
Posted: March 17, 2017, 12:25 pm
A less strenuous form of exercise known as whole-body vibration (WBV) can mimic the muscle and bone health benefits of regular exercise in mice, according to a new study. WBV consists of a person sitting, standing or lying on a machine with a vibrating platform. When the machine vibrates, it transmits energy to the body, and muscles contract and relax multiple times during each second.
Posted: March 15, 2017, 6:38 pm
Type 2 diabetes can be reversed with intensive medical treatment using oral medications, insulin and lifestyle therapies, according to a study.
Posted: March 15, 2017, 6:06 pm
Women over 75 faced a 33 percent higher chance of developing diabetes if they were taking statins, new Australian research shows. The risk increased to 51 percent for those on high doses. Clinicians are urged to be aware of the risks when prescribing and carefully monitor elderly female patients.
Posted: March 15, 2017, 1:45 pm
More than 87,000 chemicals are available commercially in the U.S., including analogues of bisphenol A (BPA), an industrial chemical that is used in consumer products. A research team has studied BPA and other chemicals and their effects on humans and animals for more than 20 years. Now, they have released Integrative Environmental Medicine, a comprehensive book outlining practical resources and tools, such as websites and smartphone apps, to help health care practitioners promote healthier choices for themselves and their patients.
Posted: March 14, 2017, 11:04 pm
A drug commonly prescribed to pregnant women with a history of delivering babies early provides no benefit. In fact, this drug may even increase the risk of developing gestational diabetes.
Posted: March 14, 2017, 11:02 pm
Researchers have created datasets that map the three-dimensional distribution and volume of the insulin-producing cells in the pancreas. The wealth of visual and quantitative information may serve as powerful reference resource for diabetes researchers.
Posted: March 14, 2017, 5:54 pm
Scientists have developed a convenient and accurate sweat-based glucose monitoring and maintenance device.
Posted: March 13, 2017, 2:24 pm
Researchers found that feeding resveratrol to obese mice over a period of 6 weeks altered the makeup of the bacteria in their intestines, improving glucose tolerance. A second experiment, involving fecal transplant from resveratrol fed mice to obese mice with insulin resistance, led to much more dramatic and rapid effects.
Posted: March 9, 2017, 6:23 pm
Researchers have long sought to understand why beta cells often fail to proliferate in people who develop insulin resistance and go on to develop type 2 diabetes. Scientists now have pinpointed one key biological mechanism that can prevent the cells from dividing successfully.
Posted: March 9, 2017, 6:22 pm
Diets higher in gluten were associated with a lower risk of developing type 2 diabetes. Study participants who ate less gluten tended to eat less cereal fiber, a known protective factor for developing type 2 diabetes.
Posted: March 9, 2017, 5:06 pm
Specific cells in the retina trigger inflammation and vision impairment associated with diabetes, according to new research.
Posted: March 9, 2017, 5:06 pm
Giving primary health care nurses a greater role in managing Type 2 Diabetes can significantly reduce delays in starting insulin treatment, a team of researchers has found.
Posted: March 9, 2017, 5:06 pm
According to a nutrition study, the so-called internal clock also influences how people with impaired glucose metabolism react to carbohydrate-rich food. E.g., in men with prediabetes, abundant consumption of foods containing starch and sugar in the evening had a negative effect on their blood glucose regulation. In comparison, in healthy study participants the timing of carbohydrate intake did not play a significant role in blood glucose regulation.
Posted: March 9, 2017, 5:05 pm
Eating healthier food could reduce greenhouse gas emissions, suggests a new study. As it turns out, some relatively small diet tweaks could add up to significant inroads in addressing climate change.
Posted: March 8, 2017, 8:44 pm
Lipocalin 2, a hormone secreted by bone cells, suppresses appetite in mice, researchers have discovered. The study findings, which reveal a new mechanism for regulating food intake and blood sugar, could lead to the development of new treatments for obesity, type 2 diabetes, and other metabolic disorders.
Posted: March 8, 2017, 6:11 pm
By comparing two strains of mice -- one that becomes obese and diabetic on a high-fat diet and another resistant to a high-fat regimen -- researchers identified genome-wide changes caused by a high-fat diet.
Posted: March 8, 2017, 1:11 pm
Babies born to mothers with cardiometabolic risk factors were less likely to develop high blood pressure if their mothers had higher levels of folate during pregnancy.
Posted: March 8, 2017, 1:10 pm
Research suggests that photographs of your food are good for a lot more than just entertaining your friends on social media -- those pictures might help improve your health and also national nutrition policy.
Posted: March 7, 2017, 6:08 pm
Researchers have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer. The study, 'AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program,' suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.
Posted: March 7, 2017, 4:28 pm
Red wine, and metformin, a drug often prescribed to fight type 2 diabetes, have many of the neuroprotective benefits of a low-calorie diet and exercise, say researchers.
Posted: March 7, 2017, 3:04 pm
Sulforaphane, a phytochemical in broccoli sprouts, is known to exert effects of cancer prevention by detoxicating chemical compounds taken into the body and by enhancing anti-oxidation ability. In the present study, experiments with mice demonstrate that sulforaphane ameliorates obesity, the conclusion based on the two functions of sulforaphane newly uncovered; amelioration of obesity through enhancing energy consumption by browning of adipocytes, and reduction of metabolic endotoxemia through improving gut bacterial flora.
Posted: March 7, 2017, 3:04 pm
Following a reduced carbohydrate diet can help to lower blood glucose levels, providing a safe and effective strategy for managing diabetes, new research suggests.
Posted: March 7, 2017, 2:13 pm
Using red blood cells modified to carry disease-specific antigens, a team of scientists have prevented and alleviated two autoimmune diseases -- multiple sclerosis (MS) and type 1 diabetes -- in early stage mouse models. This research is an exciting step toward therapeutics for autoimmune diseases, which affect an estimated 23 million Americans.
Posted: March 6, 2017, 8:17 pm
A rise in caloric consumption combined with a decrease in physical activity has contributed to a boom of metabolic diseases, such as type 2 diabetes mellitus and cardiovascular diseases.
Posted: March 6, 2017, 5:24 pm
A sweeping international effort is connecting the dots between genes in our fat cells and our risk for obesity and cardiometabolic diseases such as heart disease and type 2 diabetes. The researchers have identified approximately 90 genes found in fat that could play important roles in such diseases -- and could be targeted to develop new treatments or cures.
Posted: March 6, 2017, 4:03 pm
Girls who have their first period before age 11 are 50 percent more likely to develop gestational diabetes according to research. It is an increasingly common pregnancy complication with long-lasting health consequences for mothers and their children. The global trend towards starting puberty at a younger age is concerning, and health professionals could start to include age of first period as a marker for potential adverse health outcomes.
Posted: March 6, 2017, 2:27 pm
Researchers are planning the clinical trial of a new treatment for nonalcoholic fatty liver disease and type 2 diabetes which harnesses liver cells’ own ability to burn accumulated fats.
Posted: March 2, 2017, 2:10 pm
New study results challenge traditional ideas about the source of type 1 diabetes (T1D). T1D, previously known as juvenile diabetes, affects an estimated 1.5 million Americans and is the result of the loss of insulin-producing cells in the pancreas. The prevailing belief was that the root cause of T1D was the immune system mistakenly identifying those insulin-secreting beta cells as a potential danger and, in turn, destroying them.
Posted: March 1, 2017, 1:54 pm
A significantly higher burden of diabetes-related complications in adolescents and young adults with type 2 diabetes compared to type 1 diabetes, with greater health complications in minority youth, outlines a new report.
Posted: February 28, 2017, 6:11 pm
Some fruit flies build up tolerance to the toxin alpha-amanitin; the genetic mechanisms behind this adaptation link to an important metabolic pathway. Scientists have now used genome-wide association mapping to draw the connections for 180 fruit fly lines.
Posted: February 28, 2017, 1:42 pm
Researchers are running a Diabetes Intensive Medical Management (DIMM) 'tune up' clinic for complex type 2 diabetes patients. In a new study, the researchers report the clinic's economic benefits, which include an estimated cost avoidance of $5,287 per DIMM clinic patient over three years.
Posted: February 27, 2017, 9:16 pm
Researchers have developed an insulin release system with sustained and controllable delivery. The system combines two original technologies, SPRA and PPRX, which provide complimentary benefits for insulin delivery.
Posted: February 27, 2017, 3:07 pm
In a study on mice and another study on human pancreatic cells, researchers discover that a scientifically designed fasting diet can trigger the generation of new pancreatic cells to replace dysfunctional ones and stabilize blood glucose.
Posted: February 23, 2017, 5:42 pm
For the first time a molecular 'tipping point' has been demonstrated in Alzheimer's, linking high blood sugar with this debilitating disease.
Posted: February 23, 2017, 5:42 pm
Researchers looked at data from nearly 2,000 randomly chosen people to determine if their circadian or biological clock rhythm (chronotype) affected what they ate and at what time. Clear differences in both energy and macronutrients between the two chronotypes abound, with morning people making healthier choices throughout the day. Evening types ate less protein overall and ate more sucrose in the morning. In the evening, they ate more sucrose, fat and saturated fatty acids.
Posted: February 23, 2017, 3:27 pm
Researchers say their new study represents hope for a complication considered incurable and deadly.
Posted: February 23, 2017, 3:25 pm
A weight loss drug has reduced the risk of type 2 diabetes by 80 per cent compared to placebo, report investigators.
Posted: February 23, 2017, 3:24 pm
Physician-delivered step count prescriptions, combined with the use of a pedometer, can lead to a 20 per cent increase in daily steps, as well as measurable health benefits, such as lower blood sugar and lower insulin resistance, for patients with hypertension and/or type 2 diabetes, report researchers.
Posted: February 23, 2017, 2:21 pm
Heart disease risk factors in middle age were associated with an increased risk of dementia in later years. Smoking, high blood pressure and diabetes were all dementia risks, with diabetes in middle age raising the risk almost as much as a genetic risk factor for Alzheimer's disease. Some risk factors had a different impact in black and white participants, while genetics and smoking had a greater impact in whites.
Posted: February 22, 2017, 8:27 pm
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research.
Posted: February 22, 2017, 1:26 pm
Scientists have struggled to trace the specific biology behind diabetes-associated heart disease risk or find ways to intervene. Now, researchers have hunted down a possible culprit -- a protein called IRS-1, which is crucial for the smooth muscle cells that make up veins and arteries.
Posted: February 21, 2017, 6:07 pm
The community of microorganisms that resides in the gut, known as the microbiome, has been shown to work in tandem with the genes of a host organism to regulate insulin secretion, a key variable in the onset of the metabolic disease diabetes, new research has found.
Posted: February 17, 2017, 9:10 pm
The global proliferation of overweight and obese people and people with type 2 diabetes is often associated with the consumption of saturated fats. Scientists have found that even the one-off consumption of a greater amount of palm oil reduces the body's sensitivity to insulin and causes increased fat deposits as well as changes in the energy metabolism of the liver.
Posted: February 16, 2017, 7:39 pm
Alpha cells in the pancreas can be induced in living mice to quickly and efficiently become insulin-producing beta cells when the expression of just two genes is blocked, according to a study.
Posted: February 16, 2017, 6:03 pm
A small pilot study, in which researchers attempted to slow attacks mounted by the immune system on insulin-producing cells in type 1 diabetes, has given promising results, report investigators.
Posted: February 16, 2017, 3:55 pm
A two-drug cocktail provided better protection against diabetes-related vision loss than a single drug during testing in rat models, a team of researchers has found.
Posted: February 16, 2017, 3:40 pm
Results of a randomized clinical trial shows a periodic, five-day fasting diet designed by a esearcher safely reduced the risk factors for heart disease, cancer, diabetes and other age-related diseases.
Posted: February 16, 2017, 3:39 pm
Scientists have shown that deleting the gene for this protein, known as IP6K1, protects animal models from both obesity and diabetes.
Posted: February 15, 2017, 6:04 pm
Keeping blood sugar levels within a safe range is key to managing both type 1 and type 2 diabetes. In a new finding that could lead to fewer complications for diabetes patients, researchers have found that changes in the size of mitochondria in a small subset of brain cells play a crucial role in safely maintaining blood sugar levels.
Posted: February 15, 2017, 5:10 pm
A study has found that a pattern of gene variants associated with a body type, in which weight is deposited around the abdomen, rather than in the hips and thighs, increases the risk for type 2 diabetes and coronary heart disease, as well as the incidence of several cardiovascular risk factors. abdominal
Posted: February 14, 2017, 9:28 pm
While diet, exercise and behavior modification are essential components of obesity management, a successful long-term weight loss strategy should also include avoiding or minimizing medication-related weight gain, according to a new report.
Posted: February 14, 2017, 2:26 pm
Many genetic mutations have been linked to type 2 diabetes, but no clear genetic signature has emerged. Now, new results may explain how multiple genetic flaws can lead to the same disease: They seem to change the way certain cells in the pancreas 'read' their genes.
Posted: February 13, 2017, 8:13 pm
A new study has found that patients with diabetes suffering from the early stages of kidney disease have a deficiency of the protective 'anti-aging' hormone, Klotho.
Posted: February 13, 2017, 1:38 pm
It is now possible to reprogram cells from the liver into the precursor cells that give rise to the pancreas by altering the activity of a single gene. A team of researchers has now accomplished this feat in mice. Their results should make it feasible to help diabetic patients through cell therapy.
Posted: February 13, 2017, 1:37 pm